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Phosphomycin calcium salt (CAS No 26016-98-8), is a phosphoenolpyruvate analog antibiotic isolated from Streptomyces fradiae. It targets gram-positive and gram-negative bacteria, especially E. faecalis and E. coli. Fosfomycin concentrates in the bladder and kidney, decreasing nephrotoxicity and ototoxicity of anti-tumor agents containing platinum.
Specification
Description White to almost white powder
Identification IR: Complied
Ca Positive
Specific optical rotation –11.0°~–13.0°
PH 8.1-9.6
Water 8.5-11.5%
Heavy metals ≤0.0020%
Chloride ≤0.2%
Calcium 1,2-(Dihydroxyl propyl) phosphenate ≤1.5%
Assay(on the dried basis) 95.0-101.0%
Application
Fosfomycin calcium is suitable for the manufacture of water soluble Powders and Premixes. The appropriate excipients should be added.
Packing&Storage
25 kg/drum.
Stored below 25°C, protected from light and moisture.
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