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Product Name: Trichlormethiazide
CAS: 133-67-5
EINECS No.: 205-118-8
Density: 1.7±0.1 g/cm3
Molecular formula: C8H8Cl3N3O4S2
Molecular Weight: 380.656
Melting point: 248-250ºC
Appearance: white crystalline powder
PSA: 135.12000
Trichlormethiazide is a diuretic with properties similar to those of hydrochlorothiazide. It is usually administered for the treatment of oedema (including that which is associated with heart failure, hepatic cirrhosis and corticosteroid therapy) and hypertension. In veterinary medicine, trichlormethiazide can be combined with dexamethasone to be used on horses with mild swelling of distal limbs and general bruising. Trichlormethiazide appears to block the active reabsorption of chloride and possibly sodium in the ascending loop of Henle. This results in excretion of sodium, chloride and water, and thus acts as a diuretic